CAPTURING THE DIFFERENCES BETWEEN HUMORAL IMMUNITY IN THE NORMAL AND TUMOR ENVIRONMENTS FROM REPERTOIRE-SEQ OF B-CELL RECEPTORS USING SUPERVISED MACHINE LEARNING

Abstract Background The recent success of immunotherapy in treating tumors has attracted increasing interest in research related to the adaptive immune system in the tumor microenvironment.Recent advances in next-generation sequencing technology enabled the sequencing of whole T-cell receptors (TCRs) and B-cell receptors (BCRs)/immunoglobulins (Igs

Since the beginning of the industrial revolution, processes of different scales have contributed greatly to the pollution and waste load on the environment.More specifically, airborne pollutants associated with chemical processes have contributed greatly on the ecosystem and populations health.In this communication, we review recent activities and

According to ancient Iranian mythology, the world is depicted as a battleground between the forces of good and evil.Ahuramazda is revered as the ultimate source of goodness, while Ahriman is portrayed as the creator of all things malevolent, such as darkness, ignorance, pain, and disease.These mythological concepts have been passed down through ref

How did Renaissance listeners experience the polyphonic mass ordinary cycle in the soundscape of the church? We hypothesize that the textural differences in complexity between mass movements allowed listeners to track the progress of the service, regardless of intelligibility of the text or sophisticated musical knowledge.Building Hall or Caged Lig